Dimethyl Dicarbonate (DMPC) CAS 4525-33-1 Purity ≥99.8% (HPLC) Food Additive Preservative
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Dimethyl Dicarbonate (DMPC; Velcorin) (CAS: 4525-33-1) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Dimethyl Dicarbonate, Please contact: alvin@ruifuchem.com
| Chemical Name | Dimethyl Dicarbonate |
| Synonyms | DMPC; Velcorin; Dimethyl Pyrocarbonate; Pyrocarbonic Acid Dimethyl Ester; Methoxycarbonyl Methyl Carbonate; Methyl Pyrocarbonate |
| Stock Status | In Stock, Commercial Production |
| CAS Number | 4525-33-1 |
| Molecular Formula | C4H6O5 |
| Molecular Weight | 134.09 g/mol |
| Melting Point | 15.0~17.0℃ |
| Boiling Point | 45.0~46.0℃/5 mm Hg(lit.) |
| Flash Point | 80℃ |
| Density | 1.25 g/mL at 25℃(lit.) |
| Refractive Index n20/D | 1.392(lit.) |
| Sensitive | Moisture Sensitive |
| Water Solubility | Soluble in Water |
| Solubility | Soluble in Chloroform, a Little Soluble in Ethyl Acetate |
| COA & MSDS | Available |
| Sample | Available |
| Product Categories | Food Additive / Preservative |
| Brand | Ruifu Chemical |
| Items | Inspection Standards | Results |
| Appearance | Colorless Transparent Liquid |
Colorless Transparent Liquid |
| DMDC | ≥99.8% (GC) | >99.8% |
| Dimethyl Carbonate | ≤0.20% | 0.03% |
| Lead (Pb) | ≤2mg/kg | 0.1mg/kg |
| Proton NMR Spectrum | Conforms to Structure | Complies |
| Conclusion | The product has been tested & complies with the given specifications | |
Package: Bottle, 25kg/Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry (2~8℃) and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Hazard Symbols T - Toxic
Risk Codes
R21/22 - Harmful in contact with skin and if swallowed.
R23 - Toxic by inhalation
R34 - Causes burns
Safety Description
S18 - Handle and open container with care.
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S28 - After contact with skin, wash immediately with plenty of soap-suds.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S38 - In case of insufficient ventilation, wear suitable respiratory equipment.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs UN 2927 6.1/PG 2
WGK Germany 3
RTECS HT0362500
FLUKA BRAND F CODES 9-21
HS Code 2920900090
Hazard Class 6.1(a)
Packing Group II
Toxicity LD50 orally in Rabbit: 335 mg/kg LD50 dermal Rat > 1250 mg/kg
Dimethyl Dicarbonate (DMPC; Velcorin) (CAS: 4525-33-1), also known as Viguolin, is a kind of fruit juice beverage preservative (INS No. 242) that is allowed to be used in my country's food additive use standards. Under normal or even low temperature conditions, DMDC has a strong ability to kill many contaminating bacteria in fruit juice drinks, and its antiseptic effect is closely related to the modification and inactivation of key enzyme proteins in the bacteria by DMDC. Compared with other physical sterilization technologies, the use of DMDC is low in cost, simple and safe to operate, and does not affect the taste, smell and color of the product. It has become one of the hotspots in the research of emerging non-thermal sterilization technologies.
| Food Category No. | Food Category | Max Level (g/kg) | Note |
| 14.02.03 | Fruit and vegetable juice (nectar) drink | 0.25 | |
| 14.04 | Carbonated drinks 0.25 | ||
| 14.05.01 | Tea drinks | 0.25 | |
| 14.08 | Flavored drinks (fruit-flavored drinks only) | 0.25 | |
| 14.09 | Other drinks (only in malt fermented non-alcoholic beverages) | 0.25 |
DMDC is widely used in fruit juice and its technology is relatively mature. The sterilization effect of DMDC in fruit juice is affected by the type and strain of fruit juice, and the combined use of DMDC and other sterilization technologies can greatly improve the sterilization effect.
Dimethyl Dicarbonate (DMDC) is a colourless liquid with a slightly pungent aroma. It is primarily used as a beverage preservative, processing aid, or sterilant (Enumber 242). The application of DMDC is particularly useful when wine needs to be sterilized but cannot be sterile filtered, pasteurized, or sulfured. DMDC is also used to stabilize non-alcoholic beverages such as carbonated or non-carbonated juice beverages, isotonic sports beverages, iced teas, and flavored waters.
DMDC can penetrate cell membrane and interact with enzymes in microorganisms to block metabolism, thus achieving bactericidal effect. Even at very low concentrations, DMDC can effectively kill typical beverage spoilage bacteria without affecting the taste, flavor and color of the beverage. In addition, DMDC can be rapidly and completely hydrolyzed to trace amounts of carbon dioxide and methanol in beverages. This is also a natural ingredient in fruit juice.
Dimethyl Dicarbonate can be used in carbonated beverages, aerated or non-aerated fruit juice beverages, tea beverages, isobaric beverages and many other beverages. In Europe, the United States and some other countries, dimethyl dicarbonate is approved for widespread use in various beverages. The World Health Organization's Joint Expert Committee on Food Additives, the European Food Science Committee and the United States Food and Drug Administration-some important authorities have issued documents proving the safety of dimethyl = carbonate applications. Yeast inhibitor; preservative.
Cold sterilization of the following types of beverages: fruity beverages, high-energy beverages (with or without carbon dioxide), tea beverages (with or without carbon dioxide), fruit juice beverages (with or without carbon dioxide, fruit juice content to 100%).
Has corrosive effect on eyes and skin, directly inhaled or ingested toxic. Allowed to use (can be used as a cold fungicide for beverages under GMP conditions, with a maximum concentration of 250mg/L;FAO/WHO,2001).
Flammability; thermal decomposition of toxic and spicy stimulating gas.
